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L. F. Koroleva, L. P. Larionov, M. N. Dobrinskaya


The possibility of obtaining an alloplastic biomaterial for the implant based on doped calcium carbonate-phosphates and polycaprolactone is studied. Nanocrystalline calcium carbonate-phosphate doped with cations of iron, magnesium, potassium, zinc, manganese, and silicon intended for bone repair by drug delivery is investigated. Histological studies have revealed that samples after 60 days in a living organism are covered by a connective tissue capsule. The formation of blood vessels and nerve endings is observed in the capsule.

Keywords: biocompatible materials, dopes, calcium carbonate-phosphate, implant, osteogenesis, bone and dental tissues


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Founder:  Institute of Engineering Science, Russian Academy of Sciences (Ural Branch)
Chief Editor:  S.V. Smirnov
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