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L. F. Koroleva, M. N. Dobrinskaya, I. S. Kamantsev

DOPED NANOCRYSTALLINE CALCIUM CARBONATE-PHOSPHATE – A BIOMATERIAL FOR BONE REPAIR AND STRENGTHEINING BY DRUG DELIVERY

It is demonstrated that doped nanocrystalline calcium carbonate-phosphate is a biocompatible material that influences actively the osteogenesis bone repair in fractures, strengthening of bone tissues for drug delivery regardless of age. The introduction of doped nanocrystalline calcium carbonate-phosphates into animals increases 5 times the mechanical strength of the bone tissue. The most durable bone may occur when doped silicon, iron and magnesium nanocrystalline calcium carbonate-phosphate is introduced into an animal. The results obtained indicate the possibility of producing bioceramics based on doped nanocrystalline calcium carbonate-phosphates.

Keywords: doped calcium carbonate-phosphate; bone repair; strengthening; drug delivery
       

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Founder:  Institute of Engineering Science, Russian Academy of Sciences (Ural Branch)
Chief Editor:  E.S. Gorkunov
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